Reactivity of the Hypothalamic-Pituitary Gonadal System after 10 Minutes of Clinical Death
Abstract
When modeling a 10-minute clinical death, changes in the reproductive system were studied in white mature male rats with a weight of 180-220 g. Clinical death was modeled according to the method of V.G.Korpachev (1982). The reproductive state in intact and experimental rats was studied using morphological, morphometric, histochemical, cytophotometric biochemical research methods. At the same time, the reproductive system in index rats is in a state of moderate functioning to highlight the synthesis and secretion of testosterone.
During the period of clinical death, there is an increase in the functional activity of d-basophil cells of the adenohypophysis, the content of the Lethinating hormone provided an increase in testosterone secretion.
References
2. Karabaev A. G. The relationship between the reactivity of the autonomic nervous system and the morphofunctional activity of basophilic cells of the adenohypophysis in the post-resuscitation period //Science and Peace. – 2020. – №. 3-1. – Pp. 55-61.
3. Zarechnova N.N., Slynko T.N. The effect of mountain hypoxia on the organs of the endocrine system with insufficiency of adrenal and pancreatic hormones // Bulletin of New Medical Technologies. Electronic edition-2018. No. 4.-pp.3-10.
4. Yakimov I. A., Loginova E. S. Analysis of changes in the level of thyroid hormones in certain types of death//Journal: Almanac of modern Science and Education. - 2017.No. 6.- pp.91-92
5. Bhasin, S. Testosterone therapy in men with hypogonadism / S. Bhasin, J.P. Brito, G.R. Cunningham et al. // An Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab.– 2018. - Vol. 103 – P.1715–1744.
6. Hernández-Hernández, J.M. Kisspeptin Stimulatestion of Luteinizing Hormone (LH) during Postpartum Anestrus Continuous and Restricted Suckling / J.M. Hernández-Hernández Becerril-érez et al. // Animals (Basel). – 2021. – Vol.11 – P.1-8.
7. Mulhall, J.P. Evaluation and management of testosterone deficiency / J.P. Mulhall, L.W. Trost, R.E. Brannigan // AUA guideline. J. Urol. – 2018. - Vol. 200 – P.423–432.
8. Karabaev A.G. et al. Reactivity of the supraoptic, arcuate nucleus of the hypothalamus and the B-and D-basophilic cells of the adenohypophysis in the early postreanimation period //European Journal of Molecular & Clinical Medicine. – 2021. – Vol. 8. – No. 3. – pp. 954-957.
9. Karabaev A.G. Relationship between the reactivity of the autonomic nervous system and the morphofunctional activity of basophilic cells of the adenohypophysis in the post-resuscitation period. // Science and World International scientific journal- 2020. 3 (79). P.55-62.
10. Karabayev A. G., R. I. Isroilov. Morphofunctional Changes in Basophilic Cells of the denohypophysis during Post-resuscitation Disease // Journal of Advances in Medicine and Medical Research- 2020. 32 (8).p.130-135.
11. Mirone, V. European Association of Urology Position Statement on the role of the urologist in the management of male hypogonadism and testosterone therapy / V. Mirone, F. Debruyne, G. Dohle et al. // Eur. Urol. – 2017. - Vol. 72 – P.164–167.