Risk factors and background diseases in different variants of ischemic stroke in the elderly and senile age

Asadullaev Maksud; Vakhabova Nargiza; Asadullaev Hamidjon

doi:10.31149/ijot.v2i10.733

Asadullaev Maksud Tashkent medical Academy
Vakhabova Nargiza Tashkent medical Academy
Asadullaev Hamidjon Tashkent medical Academy

DOI: https://doi.org/10.31149/ijot.v2i10.733

Keywords: gender characteristics, risk facrisk factors and agetors and age

Abstract

Gender differences in risk factors and background diseases in elderly and senile individuals with ischemic stroke were established. Thus, it was found that senile individuals showed a decrease in the proportion of hemodynamic and lacunar stroke due to an increase in the percentage of patients with atherothrombotic stroke among both women and men. Risk factors for ischemic stroke also had their own characteristics and differed depending on age and gender. Taking into account the heterogeneity of stroke in individuals aged 44-59 years, the highest percentage (p<0.05) of Smoking, dyslipidemia (P<0.05), and psych emotional stress (p<0.05) was revealed. In elderly and senile patients, the Smoking factor significantly decreases (P<0.05). In individuals aged 44-59 years, there was a significant prevalence of atherosclerosis, arterial hypertension, CHD, TIA, rheumatism in men (p<0.05), and diabetes mellitus and heart rhythm disorders in women (p<0.05). At the same time, the prevalence of the specific weight of CHD and TIA in the structure of background diseases remained in elderly men (p<0.05).

References

Gusev E. I., Skvortsova V. I. Stroke in the Russian Federation // journal of neurology and psychiatry named after S. S. Korsakov. — 2007. Special issue-P. 7-12.

Zhulev N. M., Golovkin V. A., Dementieva L. N. Clinical and morphological features of cerebral strokes in elderly and senile people: a textbook for doctors, St. Petersburg: SPbMAPO publishing house, 2009. – 145 p.

Ivanov Yu. S. pathogenetic aspects of vascular brain failure / Yu. S. Ivanov, A. A. Mikhailenko, G. F. Semin //Seventh all-Russian Congress of neurologists-N. Novgorod, 2011. — P. 229.

Levin O. S. diagnostics and treatment of dementia in clinical practice. – Moscow: Medpress-inform, 2010. – 255 p.

Privalova M. A. the role of atrial fibrillation in the development and course of ischemic stroke in elderly and senile people // Current issues of the clinic, diagnosis and treatment of diseases in veterans of the great Patriotic war / Ed. by E. M. Ageenko. 3rd ed., reprint. St. Petersburg: Beresta, 2010, pp. 410-413.

Skvortsova V. I., Evzelman M. A. Ischemic stroke. Orel, 2006.-P. 401.

Suslina Z. A. Antithrombotic therapy of ischemic disorders of cerebral circulation. – M., 2009. – 213 p.

Suslina Z. A., Tanyashyan M. M.,. Ionova B. G. Ischemic stroke: M. Med. book, 2005. 205 p.

Baker, D.J., Wijshake, T., Tchkonia, T., LeBras- seur, N.K., Childs, B.G., van de Sluis, B., Kirkland, J.L., and van Deursen, J.M. (2011). Nature 479, 232–236.

Suliman A., Greenberg J., Chandra A. Carotid endarterectomy as the criterion standard in high-risk elderly patients // Arch Surg. – 2008. – vol.143. – P. 736-742.

Sundseth A., Faiz K.W., Ronning O.M. Factors Related to Knowledge of Stroke Symptoms and RiskFactors in a Norwegian Stroke Population. //J Stroke Cerebrovasc Dis. - 2014 May 6. – vol. 14. - p.1052-3057.

Wolfe С. Incidence of Stroke in Europe at the Beginning of the 21st Century. // The European Registers of Stroke (EROS) Investigators. Stroke. – 2009. - vol.40. – P.1557-1562.

Won SJ, Xie L, Kim SH, Tаng H, Wang Y, Мао X, et al. Influence of age on the response to fibroblast growth factor-2 treatment in a rat model of stroke. // Brain Res. – 2006. – vol.1123(l),. – P. 237-244.