A Modern Look on Rhesus-Conflict Pregnancy

  • Nazhmutdinova D. K. Doctor of medical science in 2 ND Obstetrics and gynecology department of Tashkent medical academy, Tashkent, Uzbekistan
  • Akhtamova Maftuna 3rd year master in 2nd Obstetrics and gynecology department of Tashkent medical academy, Tashkent, Uzbekistan
DOI: https://doi.org/10.17605/ijie.v4i12.2454
Keywords: Antibody, pathogenetic, pregnancy, rh-sensitization, rh-conflict, hypertension

Abstract

The article reflects modern ideas on the management of pregnant women with Rh-negative blood affiliation, the pathogenetic basis of the development of sensitization during pregnancy and modern methods of preventing Rh-conflict. The standards for providing medical care to Rh-negative women with physiological pregnancy and Rh-sensitization are presented. The role of ultrasound diagnostic methods in determining the degree of fetal anemization is shown. An algorithm for the observation of pregnant women with Rh negative blood affiliation and indications for intrauterine intravascular blood transfusion to the fetus are presented.

References

1. Sarah H.M., Hobbins C.J. Immune Fetal Hydrops. Obstetric Imaging. 2014; 124: 573–9. 7. Bidyut K., Velathupillai R., Zarco A. Red&cell alloimmuniza& tion. Obstetrics, gynaecology and reproductive medicine. 2009; 20(2): 47–56.
2. Cabral A.C.V., Reis Z.S.N., Leite H.V. et al. Cardiofemoral index as an ultrasound marker of fetal anemia in isoimmunized pregnancy. International Journal of Gynecology and Obstetrics. 2008; 100: 60–4.
3. Brennand J., Cameron A. Fetal anaemia: diagnosis and management. Best Practice & Research: Clinical Obstetrics &Gynaecology. 2007; 22(1): 15–29.
4. Mari G., Deter R.L., Carpenter R.L. et al. Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. Collaborative group for Doppler assessment of the blood velocity in anemic fetuses.Engl. J. Med. 2000; 342: 9–14.
5. Copel J.A., Grannum P.A., Green J.J. et al. Pulsed Doppler flow velocity waveforms in the prediction of fetal hematocrit of the severely isoimmunized pregnancy. Am J Obstet-Gynecol. 1989; 161: 341–4.
6. Mari G.? DettiL., Oz U. et al. Accurate prediction of fetalhemoglobin by dopper ultrasonography. Obstet Gynecol.2002; 99: 589–93.
7. Mari G. Middle cerebral artery peak systolic velocity for the diagnosis of fetal anemia: the untold story. Ultrasound Obstet Gynecol. 2005; 25: 323–30.
8. Vyas S., Nicolaides K.H., Campbell S. Doppler examination of the middle cerebral artery in anemic fetuses. Am. J. Obstet. Gynecol. 1990; 162(4): 1066–68.
9. Zimmerman R., Carpenter R.J., Durig P. et al. Longitudinal measurement of peak systolic velocity in the fetal middle cerebral artery for monitoring pregnancies complicated by red cell alloimmunisation: a prospective multicentre trial with intention&to&treat. BJOG. 2002; 109(7): 746–52.
Published
2021-12-08
How to Cite
[1]
K., N.D. and Maftuna, A. 2021. A Modern Look on Rhesus-Conflict Pregnancy. International Journal on Integrated Education. 4, 12 (Dec. 2021), 35-38. DOI:https://doi.org/10.17605/ijie.v4i12.2454.
Issue
Vol. 4 No. 12 (2021): IJIE
Section
Articles

Copyright (c) 2021 Nazhmutdinova D. K., Akhtamova Maftuna

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

In submitting the manuscript to the International Journal on Integrated Education (IJIE), the authors certify that:

  • They are authorized by their co-authors to enter into these arrangements.
  • The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
  • That it is not under consideration for publication elsewhere,
  • The publication has been approved by the author(s) and by responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
  • They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
  • They agree to the following license and copyright agreement.

License and Copyright Agreement

Authors who publish with International Journal on Integrated Education (IJIE) agree to the following terms:

  • Authors retain copyright and grant the International Journal on Integrated Education (IJIE) right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  • Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the International Journal on Integrated Education (IJIE) published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.