Predicting Preeclampsia in Early Pregnancy
Abstract
Preeclampsia and its complications, despite the rapid development of medical sciences, remain one of the most urgent problems even in developed countries. Although maternal mortality from hemorrhage and sepsis in obstetrics has been decreasing since the middle of the 20th century, the death rate from hypertensive conditions, especially preeclampsia, remains high.
References
2. Bell MJ A historical overview of preeclampsia-eclampsia. J. Obstet. Gynecol. Neonatal Nurs 39, 510–518 (2010). [PMC free article] [PubMed] [Google Scholar]
3. Hod T, Cerdeira AS & Karumanchi SA Molecular mechanisms of preeclampsia. Cold Spring Harb. Perspect. Med 5, a023473 (2015). [PMC free article] [PubMed] [Google Scholar]
4. Shahul S et al. Racial disparities in comorbidities, complications, and maternal and fetal outcomes in women with preeclampsia/eclampsia. Hypertens. Pregnancy 34, 506–515 (2015). [PMC free article] [PubMed] [Google Scholar]
5. Robillard PY, Dekker G, Iacobelli S & Chaouat G An essay of reflection: why does preeclampsia exist in humans, and why are there such huge geographical differences in epidemiology? J. Reprod. Immunol 114, 44–47 (2016). [PubMed] [Google Scholar]
6. Gray KJ, Saxena R & Karumanchi SA Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis. Am. J. Obstet. Gynecol 218, 211–218 (2018). [PMC free article] [PubMed] [Google Scholar]
In submitting the manuscript to the International Journal on Integrated Education (IJIE), the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
- That it is not under consideration for publication elsewhere,
- The publication has been approved by the author(s) and by responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
License and Copyright Agreement
Authors who publish with International Journal on Integrated Education (IJIE) agree to the following terms:
- Authors retain copyright and grant the International Journal on Integrated Education (IJIE) right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the International Journal on Integrated Education (IJIE) published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.