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The objective of the present study was to evaluate effects of dried water melon and sweet orange peel (dwmop) meal mixture on some haematological and serum indices of growing rabbits. A total of sixty rabbits 7-8 weeks old with an average weight of 630 – 645 g were randomly divided into five (5) dietary treatments with three (3) replicates and four rabbits per replicate in a Completely Randomized Design (CRD). The dietary treatments include a control diet with no DWMOP in (T1), T2 (5.0% DWMOP), T3 (10.0 % DWMOP), T4 (15.0 % DWMOP) and T5 (20.0 % DWMOP) respectively. Feed and water were offered ad libitum throughout the experiment which lasted for 12 weeks. Data obtained were used to evaluate the haematological parameters (PCV, RBC, Hb, MCV, MCH , MCHC, WBC and its differentials ), some serum biochemical indices (Albumin, globulin, total protein, creatinine, bilirubin, AST and ALT). All the haematological parameters measured were significantly (P˂0.05) different among the treatments. Total protein, bilirubin and creatinine values were not significantly (P˃0.05) influenced by DWMOP, however, glucose level and activities of ALP and AST were significantly (P˂0.05) affected by DWMOP. It was concluded that inclusion of DWMOP at 20 % in the diet of rabbits does not have any deleterious effect on the health status of the animal.


Growing rabbits Agro industrial by-products haematology serum indices

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Oluwafemi R.A, Omokore E.A and Alagbe J.O 2020. Effects of dried water melon and sweet orange peel (dwmop) meal mixture on the haematological and serum indices of growing rabbits. International Journal on Integrated Education. 3, 10 (Oct. 2020), 244-250. DOI:


  1. 1. A.O.A.C. (2000). Association of Official Analytical Chemists. Official Methods of Analysis Washington, USA, 19: 69-77.
  2. 2. Alagbe, J.O (2019). Proximate, mineral and phytochemical analysis of Piliostigma thonningii stems bark and roots. International Journal of Biological, Physical and Chemical Studies, 1(1): 1-7.
  3. 3. Afolabi, K. D., Akinsoyinii, A. O., Olajide, R. and Akinleye, S. B. (2010). Haematological parameters of the Nigerian local grower chickens fed varying dietary levels of palm kernel cake. Proc. of the 35th Annual Conf. of the Nig. Soc. for Anim. Prod., 247.
  4. 4. Adenkola, A. Y. and Dunotoye, L. A. (2004). Haematological study during pre-partum periods in brown Savanna does in Zaria, Nigeria. Annual Conf. of the Agric. Soc. of Nig. 538-540.
  5. 5. Bamishaiye, E., Muhammad, N. and Bamishaiye, O. (2009). Haematological parameters of albino rats fed on tiger nuts (Cyperuss esculentus) tuber oil meat based diet. The Internet Journal of Nutrition and Wellness, 10(1):2-6.
  6. 6. Alagbe, J.O. (2019). Haematology, serum biochemistry, relative organ weight and bacteria count of broiler chicken given different levels of Luffa aegyptiaca leaf extracts. International Journal of Advanced Biological and Biomedical Research. 7(4):382-392.
  7. 7. Bamgbose, A. M., S. D. Ogungbenro, E. E. Obasohan, M. B. Aruna and I.T. Oteko (2004). Replacement value of maize offal/cashew nut for maize in broiler diets. Annual Conference of Nigerian Society for Animal Production,. 1: 399-402.
  8. 8. Omokore, E.O and Alagbe, J.O. (2019). Efficacy of dried Phyllantus amarus leaf meal as an herbal feed additive on the growth performance, haematology and serum biochemistry of growing rabbits. International Journal of Academic Research and Development. 4(3): 97-104.
  9. 9. Musa, Bashir., Alagbe, J.O., Adegbite Motunrade Betty, Omokore, E.A. (2020). Growth performance, caeca microbial population and immune response of broiler chicks fed aqueous extract of Balanites aegyptiaca and Alchornea cordifolia stem bark mixture. United Journal for Research and Technology, 2(2):13-21.
  10. 10. Alagbe, J.O., Agubosi, O.C.P., Ajagbe, A.D, Shittu, M.D and Akintayo Balogun, O.M (2020). Performance, haematology and serum biochemical parameters of growing grass cutters fed Phyllantus amarus and Piliostigma thonningii leaf meal mixture as partial replacement for Soya bean meal. United International Journal for Research and Technology, 2(1): 14-23.
  11. 11. Bush, B. M. (1991). Interpretation of Laboratory Results for Small Animal Clinical. Blackwell Scientific publication London, UK.
  12. 12. Shittu, M.D., Adejumo, D.O., Ewuola, E.O., Alaba, O., Alagbe, J.O and Ojebiyi, O.O. (2020). Gut morphometric characteristic and ecological response of broiler starter fed varied levels of protein. Asian Journal of Animal Science, 14(1):33-39.
  13. 13. Alagbe, J.O. (2019). Performance and haemato-biochemical parameters of weaner rabbits fed diets supplemented with dried water melon (rind) meal. Journal of Dairy and Veterinary Sciences. 8(4):001-007.
  14. 14. Alagbe, J.O and Oluwafemi, R.A. (2019). Performance and haematological parameters of broiler chicks gives different levels of dried lemon grass (Cymbopogon citratus) and garlic (Allium sativum) extract. Research in: Agricultural and Veterinary Sciences. 3(2): 102 – 111.
  15. 15. Cespedes, C.L., M. El- Hafidi, N. Pavon and J. Alarcon (2008). Antioxidant and cardioprotective activities of Phenolic extract from fruits of Chilean blackberry (Aristotelia chilensis) of Maqui. Food Chemistry. 107:820-829.
  16. 16. Chanda, S. and R. Dave (2009). In vitro models for antioxidant activity evaluation and some medicinal plants processing antioxidant properties. An overview. African Journal of Microbiology Research, 3:981-996.
  17. 17. Cheeke, P.R., P.J., Manning, D. H. Ringler and C.E. Newcomber.(1994) Rabbit Feeding and Nutrition. The Biology of the Laboratory Rabbit. 2:321-340.
  18. 18. Alagbe, J.O and Oluwafemi, R.A. (2019). Hematology and serum biochemical indices of growing rabbits fed diet supplemented with different levels of Indigofera zollingeriana leaf meal. Progress in Chemical and Biochemical Research. 2(4): 170-177.
  19. 19. Oluwafemi, R.A., Isiaka Olawale and Alagbe, J.O. (2020). Recent trends in the utilization of medicinal plants as growth promoters in poultry nutrition- A review. Research in: Agricultural and Veterinary Sciences. 4(1): 5-11.
  20. 20. Alagbe, J.O. (2017). Effect of feeding different levels of Tridax procumbens meal on the performance, carcass characteristics and blood profile of growing cockerels. Scholarly Journal of Agricultural Science. 7(1):20-26.
  21. 21. Chineke, C. A., Ologun, A. G. and Ikeobi, C. O. N. (2006). Haematological parameters in rabbit breeds and crosses in humid tropics. Pakistan Journal of Biological Sciences, 9:2102-2106.
  22. 22. Cho, J.M., Seddon, B., Roser, E.C., Willet and S.E. Hankinson (2004). Prospective study of intake of fruits, vegetables, vitamins and carotenoids and risk of age, 6:883-892.
  23. 23. Del Rio, D., Rodriguez- Mateos, A, Spenser, J.P.E., Tognolini, M. and Borges, G. Crozier (2013). Dietary phenolics in human health: structures, bioavailability and evidence of protective effects against chronic diseases. Antioxidants and Redox Signaling, 18:1818-1892.
  24. 24. Dreosti, (2000). Recommended dietary intake levels for phytochemicals. Feasible or Fanciful. Asia Pacific Journal of Clinical Nutrition, 9:119-122.
  25. 25. Duncan, D.B. (1955). Multiple Range and Multiple F-Test Biometrics 11: 1-42.
  26. 26. Alagbe, J.O. (2017). Nutrient evaluation of sweet orange (Citrus sinensis) fruit peel as a replacement for maize in the diets of weaner grass cutters. Scholarly Journal of Agricultural Science. 6(8):277-282.
  27. 27. Egbuonu, A.C.C. (2015). Assessment of some anti-nutrient properties of water melon rind and seeds. Research Journal of Environmental Sciences. 9: 225-232.
  28. 28. Esonu, B. O., Emenalom, O. O., Udedibie, A. B. I., Berbert, U., Ekpor, C. F., Okoli, E. C. and Iheukwumere, F. C. (2001). Performance and chemistry of weaner pigs fed raw mucuna bean (Velvet bean) meal. Trop. Anim. Prod. Invest., 4:49-54.
  29. 29. Ewuola, E. O., Sokunbi, A. O., Alaba, O., Omotoso, J. O. and Omoniyi, A. B. (2010). Haematology and serum biochemistry of weaned rabbits fed dietary prebiotics and probiotics. Annual Conf. of the Nig. Soc. for Anim. Prod., 147.
  30. 30. Fila, W.A, Ifam, E.H., Johnson, J.T., Odey, M.O, and Effiong, E.E. (2013). Comparative proximate compositions of watermelon Citrullus Lanatus, Squash cucurbita pepo’l and Rambutan, Nephelium Lappaceum. International Journal of Science and Technology, 2(1): 81-88.
  31. 31. Gwana, A.M., Bako, M.M., Bagudu, B.Y., Sadiq, A.B. and Abdullahi, M.M. (2014). Determinations of phytochemical, vitamin, mineral and proximate compositions of varieties of water melon seeds cultivated in Borno State, north-Eastern Nigeria. International Journal of Nutrition and food Sciences, 3(4): 238-245.
  32. 32. Hafiza, M.A., B. Parreen, R. Ahmad and K. Hamid (2002). Phytochemical and antifungal screening of Medicago sativa and Zinnia elegan. Online Journal of Biological Sciences, Vol-2, pp-130-132.
  33. 33. Hassan, H.S., Sule, M.I., Musa, A.M and Musa, K.Y (2012). Anti-inflammatory activities of crude saponin extracts from five Nigerian medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines, 9:250 -255.
  34. 34. Ibrahim H, Hassan M.R., Abdu, S.B., Chidinma, F., Aliyu, Z.I., (2018). Blood biochemical profile and carcass characteristics of weaner rabbits fed varying levels of Gamba grass (Andropogon gayanus Kunth) forage. Nigeria Journal of Animal Science. 20 (4): 522- 560.
  35. 35. Ikram, U.H., Sikander A., Qadeer M.A., and Javed I. (2002). Citric acid fermentation by mutant strain of Aspergillus niger GCMC-7, using molasses based medium. Electronic Journal of Biotechnology, 5(2):717- 3458.
  36. 36. Iheukwumere, F. C., Herbert, U., Iloeje, M. U. and Onyekwere, M. (2007). Physiological response of West African Dwarf does to progesterone injections: Haematology and serum biochemistry. Annual Conf. of Nig. Sco. For Anim. Prod., 79-82.
  37. 37. Ipinloju, Z.A. (2000). Introduction to Poultry Animal Production. 28(1):20. Production in Nigeria, Bodija, Oyo state.
  38. 38. Jenkins, J.R. (1999). Feeding recommendations for the horse rabbit: Veterinary Clinics of North America: Exotic Animal Practice. 2:143. W.B. Saunders Company, Philadelphia.
  39. 39. Johnson, J.T., Iwang, E.U., Hemen, J.T., Odey, M.O. and Effiong, E.E. (2012). Evaluation of anti-nutrients contents of watermelon Citrullus lanatus. Annals of Biological Research 3(11): 5145-5150.
  40. 40. Keyvan, D.H.J., Diamen, D., L., Raimo, H. (2007). Chemical composition and antioxidative activity of moldavian balm (Dracocephalum moldavica L.) extracts. LWT-Food Science and Technology, 40:1655-1663.
  41. 41. Kasolo, J.N., Gabriel, S., Bimenya, L.O, Joseph, O and Ogwal-Okeng, J.W (2010). Phytochemical and uses of Moringa leaves in Ugandan rural coomunities. Journal of Medicinal Plants Research, 4(9):753-757.
  42. 42. Kumar, V and Amit, K (2010). Dietary role of phytate and phytase. Retrieved October 6, 2019 from http//
  43. 43. McDonald P., Edwards R.A., Greenhalgh J.F.D., Morgan C.A. (2002). Animal Nutrition (6thEd.). Pearson Education (Singapore) Press Ltd New Delhi, India. 693.
  44. 44. Megias M.D., Martinez Teruela A., Gallego J.A., Nuñez J.M. (1993). Chemical changes during the ensiling of orange peel. Animal Feed Science and Technology, 1993;43 (3-4):269-274.
  45. 45. Mitruka, B. M. and Rawnsley, H. M. (1977). Clinical, biochemical and haematological reference values in normal and experimental animals. Masson Publishing, USA, Inc., 83:134-135.
  46. 46. Neal R.W. and Stovers F.A. (1999). Rabbit management in the tropics production, processing, utilization, marketing, economics, research and future prospects. Living books series, UK, 20–24.
  47. 47. NRC (National Research Council). (1991). Micro- livestock little known small ruminants with a promising economic future. National Academy Press, Washington D.C .Pp 192-282.
  48. 48. Olatunji, A.K., Alagbe, J.O., Hammed. M.A. (2016). Effects of varying level of Moringa olifera on the performance of weaner rabbits. International Journal of Science and Research. 5: 6-7.
  49. 49. Olayinka, B.U., Etejere, E.O. (2018). Proximate and chemical composition of (Citrullus lanatus) and Cucumber. International Food Research Journal. 25(3): 1060-1066.
  50. 50. Oluremi, B.E. (2008). The role of vitamins and other nutrients in broiler diets. Tropical AnimalHealth Production, 11:199–202.
  51. 51. Perkins-veazie, P., Collins, J.K. (2004). Flesh quality and lycopene stability of fresh-cut watermelon. Postharvest Biology and technology, 31:159-166.
  52. 52. Stevenson, D.E., and Hurst, R.D. (2007). Polyphenolic Photochemical-Just antioxidants or much more? Cellular and Molecular Life Sciences, 64(22):2900-2916.
  53. 53. Serres, H. (1992). Manual of Pig Production in the Tropics. CAB International, Wellington. 14-
  54. 54. Togun, V. A., Oseni, B. S. A., Ogundipe, J. A., Arewa, T. R., Hammed, A. A., Ajonijebu, D. C., Oyeniran, A., Nwosisi, I. and Mustapha, F. (2007). Effects of chronic lead administration on the haematological parameters of rabbit – a preliminary study. Conf. of the Agric. Soc. of Nig., 41: 341-342.
  55. 55. Unigwe, C.R., Balogun, F.A., Okorafor, U.P., Odah, S.I., Abonyi, F.O., Olona, J.F. (2016). Effect of neem leaf (Azadirachta indica) meal on growth performance and hematology of rabbits. World Scientific News. 55:51-62.
  56. 56. Williams, R.J. and Spencer, J.P. (2012). Flavonoids, cognition and dementia: actions, mechanisms and potential therapeutic utility of Alzheimer disease. Free Radical Biology and Medicine, 2(52):35-45.