Modern Approach to Miscarriage of Pregnancy

  • Kamilova Iroda Abdurasulovna DSc., Assistant of the Department of Obstetrics and Gynecology, Tashkent Medical Academy, Tashkent, Uzbekistan
  • Sharipova Dildora Shuxratovna Master of the 1st year of study at the Department of Obstetrics and Gynecology of the Tashkent Medical Academy. Tashkent, Uzbekistan
DOI: https://doi.org/10.17605/ijie.v6i6.4482
Keywords: miscarriage, progesterone therapy, premature birth, abortion

Abstract

This review article is devoted to the problem of miscarriage, premature birth, developmental etiopathogenesis and modern approaches to the management and treatment of this pathology.

References

1. Sidelnikova V.M., Sukhikh G.T. Miscarriage: a guide for practitioners. M.: MIA, 2010.
2. Radzinsky V.E., Solovieva A.V., Olenev A.S. Miscarriage. What's in the future? reproductive medicine. 2014;3-4(20):8-10.
3. Mikhalevich S.I., Grishkevich A.N., Markovskaya T.V., Grakovich L.G. Recurrent miscarriage: a social problem, medical solutions. Medical news. 2012; 2:12.
4. Tirskaya, Yu.I. Fetal loss syndrome / Yu.I. Tirskaya, E.B. Rudakova, I.A. Shakina // Emergency Medicine. - 2010. - No. 3. - S. 22-26.
5. Carp Howard, J.A. Recurrent pregnancy loss: causes, controversies and treatment / J.A. Carp Howard // Informa UK ltd. – 2007. – 290 p.
6. Alijotas-Reig, J. Current concepts and new trends in the diagnosis and management of recurrent miscarriage / J. Alijotas-Reig, C. Garrido-Gimenez // Obstet. Gynecol. Surv. – 2013. – V. 68(6). – P. 445-466.
7. Apolikhina, I.A. Causes of miscarriage / I.A. Apolikhina, M.G. Shneiderman, T.A. Teterina, E.A. Gorbunova // Gynecology. -2013. - T. 15 (5). - P. 60-65
8. Levkovich, M.A. Immunological mechanisms of the threat of termination of pregnancy / M.A. Levkovich // Allergology and Immunology. - 2009. - T. 10, No. 2. – P. 247.
9. Sidelnikova, V.M. Preparation and management of pregnancy in women with habitual miscarriage / V.M. Sidelnikov. - 3rd ed. – M.: MEDpressinform, 2013. – 224 p.
10. Kwinecka-Dmitriew, B. Frequency of chromosomal aberrations in material from abortions / B. Kwinecka-Dmitriew, M. Zakrzewska, A. Latos-Bieleńska, J. Skrzypczak // Ginekol. Pol. – 2010. – V. 81(12). – P. 896-901.
11. Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss. Siobhan Quenby, Ioannis D Gallos, Rima K Dhillon-Smith, Marcelina Podesek, Mary D Stephenson, Joanne Fisher, Jan J Brosens, Jane Brewin, Rosanna Ramhorst, Emma S Lucas, Rajiv C McCoy, Robert Anderson, Shahd Daher, Lesley Regan, Maya Al-Memar, Tom Bourne, David A MacIntyre, Raj Rai, Ole B Christiansen, Mayumi Sugiura-Ogasawara, Joshua Odendaal, Adam J Devall, Phillip R Bennett, Stavros Petrou, Arri Coomarasamy - Interpregnancy interval and adverse pregnancy outcomes among pregnancies following miscarriages or induced abortions in Norway (2008-2016): A cohort study.
12. Page JM, Silver RM. Genetic Causes of Recurrent Pregnancy Loss. Clin Obstet Gynecol. 2016;59(3):498-508. DOI:10.1097/GRF.0000000000000217.
13. Fetisova I.N., Malyshkina A.I., Ratnikova S.Yu., et al. Chromosomal aberrations as a cause of recurrent miscarriage. Bulletin of the Ivanovo Medical Academy. 2019;24(4):39-43.
14. Shah D, Nagarajan N. Luteal insufficiency in first trimester. Indian J Endocrinol Metab. 2013;17(1):44-9. DOI:10.4103/2230-8210.107834
15. Lata K, Dutta P, Sridhar S, et al. Thyroid autoimmunity and obstetric outcomes in women with recurrent miscarriage: a case-control study. Endocr Connect. 2013;2(2):118-24. DOI:10.1530/EC-13-0012.
16. Sotnikova N.Yu., Antsiferova Yu.S., Kroshkina N.V., Voronin D.N. The role of innate immune cells in ensuring the success of early pregnancy. Journal of Obstetrics and Women's Diseases. 2013;62(2):151-9.
17. Batrak N.V., Malyshkina A.I., Kroshkina N.V. Immunological aspects of recurrent miscarriage. Obstetrics and gynecology. 2014; 12:10-4.
18. Cao C-J, Wang Y-F, Fang D-M, Hu Y. Relation between mycoplasma infection and recurrent spontaneous abortion. Eur Rev Med Pharmacol Sci. 2018;22(8):2207-11. DOI:10.26355/eurrev_201804_14805.
19. Dimitriadis E, Menkhorst E, Saito S, et al. Recurrent pregnancy loss. Nat Rev Dis Primers. 2020;6(1):98. DOI:10.1038/s41572-020-00228-z.
20. Batrak N.V., Malyshkina A.I. Risk factors for recurrent miscarriage. Bulletin of the Ivanovo Medical Academy. 2016;21(4):37-41.
21. Nazarova A.O., Malyshkina A.I., Nazarov S.B., Boyko E.L. Risk factors for threatening preterm birth: results of a clinical and epidemiological study. Obstetrics and gynecology. DOI:10.18565/aig.2020.6.43-48.
22. Tetruashvili N.K., Agadzhanova A.A. Dydrogesterone in the treatment of threatened and recurrent miscarriage. Medical advice. 2018;(13) 68-72. DOI: 10.21518/2079-701Х-2018-13-68-72.
23. Shikh E.V. Pharmacotherapy during pregnancy. Moscow: GEOTAR-Media; 2019. 208 p. Access mode:
https://www.rosmedlib.ru/book/ISBN9785970449783.html.
25. 24. Serov V.N., Sukhikh G.T. Rational pharmacotherapy in obstetrics, gynecology and neonatology. VOLUME 2. Gynecology. 2nd ed. Moscow: Litter; 2010. P. 557-559. Access mode: https://akusher-lib.ru/books/.
26. 14. Page J.M, Silver R.M. Genetic Causes of Recurrent Pregnancy Loss. Clinical Obstetrics and Gynaecology. 2016;59(3):498- 508. https://doi.org/10.1097/GRF.0000000000000217.
27. Flynn H, Yan J, Saravelos SH, Li TC. Comparison of reproductive outcome, including the pattern of loss, between couples with chromosomal abnormalities and those with unexplained repeated miscarriages. The Journal Obstetrics and Gynaecology Research. 2014;40(1):109-16. https://doi.org/10.1111/jog.12133.
28. Lata K, Dutta P, Sridhar S, Rohilla M, Srinivasan A, Prashad GR et al. Thyroid autoimmunity and obstetric outcomes in women with recurrent miscarriage: a case-control study. Endocrine Connections. 2013;2(2):118-124. https://doi. org/10.1530/EC-13-0012.
29. Turocy JM, Rackow BW. Uterine factor in recurrent pregnancy loss. Seminars in Perinatology. 2019;43(2):74- 79. https://doi.org/10.1053/j.semperi.2018.12.003.
30. Seckin B, Sarikaya E, Oruc AS, Celen S, Cicek N. Office hysteroscopic findings in patients with two, three, and four or more, consecutive miscarriages. The European Journal of Contraception & Reproductive Health Care. 2012;17(5):393-398. https://doi.org/10.3109/13625187.20 12.698767.
31. Galamb Á, Pethő B, Fekete D, Petrányi G, Pajor A. A méhüreg anatómiai rendellenességei habituális vetélőkben [Uterine anomalies in women with recurrent pregnancy loss]. Orvosi Hetilap. 2015;156(27):1081-1084. https://doi.org/10.1556/650.2015.30136.
32. Saribegova V.A., Tetruashvili N.K., Krechetova L.V. The course and outcomes of pregnancy in women with idiopathic recurrent miscarriage using immunocytotherapy. Obstetrics and gynecology. 2017; 8:68–73.
33. https://dx.doi.org/10.18565/aig.2017.8.68-73.
34. Podzolkova N.M., Skvortsova M.Yu., Sheveleva T.V. Miscarriage. Guide for doctors. Moscow: GEOTAR-Media; 2013:136.
35. D’Ippolito S, Ticconi С, Tersigni C, Garofalo S, Martino C, Lanzone A et al. The pathogenic role of autoantibodies in recurrent pregnancy loss. American Journal of Reproductive Immunology. 2020;83(1):e13200. https:// doi.org/10.1111/aji.13200.
36. Khalid AS, Joyce C, O’Donoghue K. Prevalence of subclinical and undiagnosed overt hypothyroidism in a pregnancy loss clinic. Irish medical journal. 2013;106(4):107-110.
37. Zhang HX, Qin YZ, Liu WH, Hao R. Hypothyroidism and first trimester spontaneous miscarriages. Clinical and Experimental Obstetrics and Gynecology. 2014;41(2):182- 185. PMID: 24779248.
38. Kust A.V., Kozelkova E.V., Sadygova A.V., Borzova N.Yu., Smirnova A.V., Batrak N.V. Infectious status in women with a threatened miscarriage and a history of recurrent miscarriage. Russian immunological journal. 2019;22(2-1):362-364. https://doi.org/10.31857/S102872210006628-5.
Published
2023-06-09
How to Cite
[1]
Abdurasulovna, K.I. and Shuxratovna, S.D. 2023. Modern Approach to Miscarriage of Pregnancy. International Journal on Integrated Education. 6, 6 (Jun. 2023), 130-134. DOI:https://doi.org/10.17605/ijie.v6i6.4482.
Issue
Vol. 6 No. 6 (2023): International Journal on Integrated Education (IJIE)
Section
Articles

In submitting the manuscript to the International Journal on Integrated Education (IJIE), the authors certify that:

  • They are authorized by their co-authors to enter into these arrangements.
  • The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
  • That it is not under consideration for publication elsewhere,
  • The publication has been approved by the author(s) and by responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
  • They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
  • They agree to the following license and copyright agreement.

License and Copyright Agreement

Authors who publish with International Journal on Integrated Education (IJIE) agree to the following terms:

  • Authors retain copyright and grant the International Journal on Integrated Education (IJIE) right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  • Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the International Journal on Integrated Education (IJIE) published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.