Intraoperative express diagnostics of the effectiveness of antiparasitic treatment during Echinococectomy
Abstract
To increase the reliability, simplify the assessment of the viability of protoscolexes, significantly reduce the duration of testing, we have developed and used a simple and reliable "Method for determining the effectiveness of antiparasitic treatment of echinococcal cysts" in this study, which allows to determine the viability of protoscolexes during the operation and in a short time. The essence of the invention lies in the fact that after antiparasitic treatment of an echinococcal cyst, 2 drops of wash water are poured into the well of a glass slide, followed by microscopy at 1000-fold magnification. Microscopic examination assesses the motor activity and morphostructure of the parenchyma of protoscolexes and acephalocysts. Lack of motor activity in combination with destruction and smoothing of the parenchyma structure, destruction of the crown of the protoscolex hooks indicate irreversible destructive changes and death of the parasite, in these cases antiparasitic treatment is recognized as effective. Revealing even insignificant motor activity, as well as maintaining the shape, morphostructure of the parenchyma, demonstrate the viability of the protoscolex and indicate the ineffectiveness of antiparasitic treatment
References
Ahmadi N.A., Bodi F. Clinical Presentation, Localization and Morphology of Hepato-Pulmonary Hydatid Cysts in Patients Operated in Tehran. World Applied Sciences Journal 12 (9): 1544-1548, 2011.
Babuci Stanislav Argumentarea patogenetică şi clinico-morfologică a tratamentului medico-chirurgical în hidatidoza pulmonară la copil.:Autoreferat al tezei de doctor habilitat în medicină. CHIŞINĂU 2005. 23 p.
Jamshed Shamsiev The experience of using glycerine during the processing of larval cyst cavity Medical Health and Science Journal. 2010. 4. 4. p. 54-59.
Shamsiyev A.M., Shamsiyev J.A., Kurbaniyazov Z.B., Rakhmanov К.Е., Davlatov S.S. Prevention and pharmacotherapy of liver echinococcosis // Science and education issues. 2017/12/4. p. 159.
Copyright (c) 2021 Shamsiev Jamshid Azamatovich, Shamsiev Azamat Muhitdinovich, Babajanov Nurbek Maxsudovich
This work is licensed under a Creative Commons Attribution 4.0 International License.
In submitting the manuscript to the International Journal on Integrated Education (IJIE), the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
- That it is not under consideration for publication elsewhere,
- The publication has been approved by the author(s) and by responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
License and Copyright Agreement
Authors who publish with International Journal on Integrated Education (IJIE) agree to the following terms:
- Authors retain copyright and grant the International Journal on Integrated Education (IJIE) right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the International Journal on Integrated Education (IJIE) published version of the work (e.g., post it to an institutional repository or edit it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) before and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
